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B Western blot analysis demonstrated the upregulation of c Jun, phosphorylated c Jun Ser63 and Ser73 and cyclin D1 in the stable PIN1 transfected NP69 cells tamoxifen package insert Again, the intent is not to be polemical, but the stakes are so high that we need more than carefully couched scientific wording to help ensure that patients are not harmed by tamoxifen DDI